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Peptide record

TPDB09807

Antibacterial Blood-Brain Barrier Cell-penetrating Peptides Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09807
Antibacterial Blood-Brain Barrier Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia B3Pred BBPpredict CPPsite3.0 PerseuCPP
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Blood-Brain Barrier, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, B3Pred, and other sources, with an available 3D structural model.
Sequence
AGYLLGKINLKPLAALAKKIL
Physicochemical Analysis
C106H186N26O24
RDCEQHMFSTWV
L
2208.80
10.64
4
0
13
+4
-0.75
0.771
167.62
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
67.46
2
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
6
L
4
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 6 K: 4 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
21
C106H186N26O24
2208.80
10.64
+4
-0.75
0.771
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria. | J Pept Sci | 2015
Evidence 2 Activity

Activity

100% Killing
Toxicity
256 µg/mL
Cytotoxic
100% Killing | 256 | µg/mL | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria. | J Pept Sci | 2015