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Peptide record

TPDB09804

Antibacterial Antifungal Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09804
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RWCVYAYVRVAGVLVRYRRCW
Physicochemical Analysis
C124H188N38O25S2
NDEQHIKMFPST
RV
2675.22
10.44
5
0
13
+5
-3.49
0.229
97.14
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
15595
582.94
5
Residue Composition
number
2
A
5
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
3
Y
5
V
Amino Acid Distribution
A: 2 R: 5 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 3 V: 5
Chemical Descriptors
21
C124H188N38O25S2
2675.22
10.44
+5
-3.49
0.229
Evidence Records 5 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
0% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The characteristic region of arenicin-1 involved with a bacterial membrane targeting mechanism. | Biochem Biophys Res Commun | 2011
Evidence 2 Activity

Activity

7% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
7% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The characteristic region of arenicin-1 involved with a bacterial membrane targeting mechanism. | Biochem Biophys Res Commun | 2011
Evidence 3 Activity

Activity

32% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
32% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The characteristic region of arenicin-1 involved with a bacterial membrane targeting mechanism. | Biochem Biophys Res Commun | 2011
Evidence 4 Activity

Activity

45% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
45% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The characteristic region of arenicin-1 involved with a bacterial membrane targeting mechanism. | Biochem Biophys Res Commun | 2011
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis