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Peptide record

TPDB09791

Antibacterial Antifungal Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09791
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFMKYIGPLIPHAVKAIKKLI
Physicochemical Analysis
C114H189N27O23S1
RNDCEQSTW
IK
2337.98
10.64
5
0
12
+4
0.91
0.667
134.76
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
63.73
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
4
I
2
L
4
K
1
M
1
F
2
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 4 L: 2 K: 4 M: 1 F: 1 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
21
C114H189N27O23S1
2337.98
10.64
+4
0.91
0.667
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
50% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. | Peptides | 2005
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis