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Peptide record

TPDB09769

Antibacterial Antifungal Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09769
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GIWKTIKSMGKVFAGAILQNL
Physicochemical Analysis
C106H175N27O26S1
RDCEHPY
GIK
2275.78
10.84
3
0
11
+3
-1.26
0.538
116.19
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
241.68
4
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
1
Q
3
G
0
H
3
I
2
L
3
K
1
M
1
F
0
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 3 L: 2 K: 3 M: 1 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
21
C106H175N27O26S1
2275.78
10.84
+3
-1.26
0.538
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
50% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties of brevinin-2-related peptide and its analogs: Efficacy against multidrug-resistant Acinetobacter baumannii | Chem Biol Drug Des | 2009
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis