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Peptide record

TPDB09756

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09756
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKVFKKAEKMIRNIRNKIVK
Physicochemical Analysis
C123H213N37O26S1
DCQGHLPSTY
K
2658.34
11.76
9
1
9
+8
7.24
-0.919
88.10
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
206.90
2
Residue Composition
number
1
A
2
R
2
N
0
D
0
C
1
E
0
Q
0
G
0
H
3
I
0
L
7
K
1
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 2 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 3 L: 0 K: 7 M: 1 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
21
C123H213N37O26S1
2658.34
11.76
+8
7.24
-0.919
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>250 µM
Hemolytic Cytotoxic
50% Hemolysis | >250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms. | Sci Rep | 2018