Back to search

Peptide record

TPDB09754

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09754
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KQKLAKLKAKLQKLKQKLAKL
Physicochemical Analysis
C114H215N33O25
RNDCEGHIMFPSTWYV
K
2448.17
11.41
9
0
9
+9
6.78
-0.829
125.71
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
3
Q
0
G
0
H
0
I
6
L
9
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 0 H: 0 I: 0 L: 6 K: 9 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C114H215N33O25
2448.17
11.41
+9
6.78
-0.829
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>>600 µM
Hemolytic Cytotoxic
50% Hemolysis | >>600 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers. | Proc Natl Acad Sci U S A | 2013