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Peptide record

TPDB09749

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09749
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKLAGLAKKWAGLAKKLAGLA
Physicochemical Analysis
C101H178N28O22
RNDCEQHIMFPSTYV
AK
2136.70
11.21
6
0
12
+6
0.30
0.205
121.43
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
257.41
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
5
L
6
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 5 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
21
C101H178N28O22
2136.70
11.21
+6
0.30
0.205
Evidence Records 1 records
Evidence 1 Activity

Activity

13% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
13% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activities and structures of two linear cationic peptide families with various amphipathic beta-sheet and alpha-helical potentials | Antimicrob Agents Chemother | 2005