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Peptide record

TPDB09748

Antibacterial Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09748
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KKFLHSAKKWLKAFVKLFKNW
Physicochemical Analysis
C133H203N33O24
RDCEQGIMPTY
K
2648.28
11.29
8
0
11
+7
-0.60
-0.429
79.05
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
415.36
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
3
L
7
K
0
M
3
F
0
P
1
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 3 K: 7 M: 0 F: 3 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
21
C133H203N33O24
2648.28
11.29
+7
-0.60
-0.429
Evidence Records 5 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992
Evidence 2 Activity

Activity

16% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
16% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992
Evidence 3 Activity

Activity

29% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
29% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992
Evidence 4 Activity

Activity

41% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
41% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis