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Peptide record

TPDB09715

Antibacterial Cell-penetrating Peptides Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09715
Antibacterial Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0 PerseuCPP
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CPPsite3.0, and other sources, with an available 3D structural model.
Sequence
AAYLLAKINLKALAALAKKIL
Physicochemical Analysis
C106H188N26O24
RDCEQGHMFPSTWV
A
2210.82
10.64
4
0
16
+4
-1.73
1.143
181.90
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
67.40
2
Residue Composition
number
7
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
6
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 6 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
21
C106H188N26O24
2210.82
10.64
+4
-1.73
1.143
Evidence Records 2 records
Evidence 1 Activity

Activity

40% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
40% Hemolysis | 512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria. | J Pept Sci | 2015
Evidence 2 Activity

Activity

100% Killing
Toxicity
128 µg/mL
Cytotoxic
100% Killing | 128 | µg/mL | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria. | J Pept Sci | 2015