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Peptide record

TPDB09708

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09708
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SLWETIKNAGKGFIQNLDKIR
Physicochemical Analysis
C110H179N31O31
CHMPYV
IK
2431.82
10.31
4
2
8
+2
3.54
-0.533
97.62
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
226.17
5
Residue Composition
number
1
A
1
R
2
N
1
D
0
C
1
E
1
Q
2
G
0
H
3
I
2
L
3
K
0
M
1
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 1 C: 0 E: 1 Q: 1 G: 2 H: 0 I: 3 L: 2 K: 3 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
21
C110H179N31O31
2431.82
10.31
+2
3.54
-0.533
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9.38 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (M
Evidence 2 Activity

Activity

MIC
Antibacterial
21.88 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Ran
Evidence 3 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

dbAMP DRAMP

Other

(MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Rana box, this peptide is much less hemolytic than Nigroain-K2 with a Rana b
Evidence 4 Activity

Activity

MIC
Antifungal
9.38 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (M
Evidence 5 Activity

Activity

MIC
Antifungal
21.88 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Ran
Evidence 6 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Rana box, this peptide is much less hemolytic than Nigroain-K2 with a Rana b
Evidence 7 Activity

Activity

MIC
Antiparasitic
9.38 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (M
Evidence 8 Activity

Activity

MIC
Antiparasitic
21.88 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Ran
Evidence 9 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

DRAMP

Other

(MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Rana box, this peptide is much less hemolytic than Nigroain-K2 with a Rana b
Evidence 10 Activity

Activity

MIC
Antiviral
9.38 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (M
Evidence 11 Activity

Activity

MIC
Antiviral
21.88 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against S. aureus ATCC25923 (MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Ran
Evidence 12 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

DRAMP

Other

(MIC 9.38 ug/ml), B. subtilis (MIC 21.88 ug/ml), C. albicans ATCC2002 (32.74 ug/ml), and E. coli ML-35P (MIC 37.5 ug/ml). Without the Rana box, this peptide is much less hemolytic than Nigroain-K2 with a Rana b