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Peptide record

TPDB09676

Antibacterial Antifungal Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09676
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFMKYIGPLIPHKVKAISDLI
Physicochemical Analysis
C112H182N26O26S1
RNCEQTW
I
2340.90
10.06
4
1
11
+2
1.45
0.562
130.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
63.65
2
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
1
H
4
I
2
L
3
K
1
M
1
F
2
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 4 L: 2 K: 3 M: 1 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
21
C112H182N26O26S1
2340.90
10.06
+2
1.45
0.562
Evidence Records 2 records
Evidence 1 Activity

Activity

32% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
32% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. | Peptides | 2005
Evidence 2 Activity

Activity

50% Cell death
Toxicity
280 µM
Cytotoxic
50% Cell death | 280 | µM | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. | Peptides | 2005