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Peptide record

TPDB09668

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09668
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KKFFLKVLTKIRCKVAGGCRT
Physicochemical Analysis
C109H190N32O24S2
NDEQHMPSWY
K
2397.03
11.08
7
0
8
+7
2.67
0.105
88.10
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
5.21
4
Residue Composition
number
1
A
2
R
0
N
0
D
2
C
0
E
0
Q
2
G
0
H
1
I
2
L
5
K
0
M
2
F
0
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 5 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
21
C109H190N32O24S2
2397.03
11.08
+7
2.67
0.105
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 256 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Effects of thioredoxin: SUMO and intein on soluble fusion expression of an antimicrobial peptide OG2 in Escherichia coli. | Protein Pept Lett | 2013
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
2 %
Hemolytic
Hemolytic_activity: [Ref.22670762]7%±2% hemolysis at 2-256 µg/mL against porcine red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
Protein Pept Lett. 2013 Jan 20(1):54-60.