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Peptide record

TPDB09653

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09653
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LLLGIKYKKIGANNFREVKK
Physicochemical Analysis
C109H186N30O26
DCQHMPSTW
K
2332.86
10.76
6
1
9
+5
4.17
-0.370
117.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
63.87
3
Residue Composition
number
1
A
1
R
2
N
0
D
0
C
1
E
0
Q
2
G
0
H
2
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
20
C109H186N30O26
2332.86
10.76
+5
4.17
-0.370
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
128 µM
Cytotoxic
0% Cytotoxicity | 128 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020