Peptide record

TPDB09648

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09648
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
QQCRRPLYCRRRWSHPQFEK
Physicochemical Analysis
C116H180N42O28S2
ANDGIMTV
R
2675.09
11.18
7
1
4
+5
5.83
-1.910
19.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
7115
265.97
7
Residue Composition
number
0
A
5
R
0
N
0
D
2
C
1
E
3
Q
0
G
1
H
0
I
1
L
1
K
0
M
1
F
2
P
1
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 2 E: 1 Q: 3 G: 0 H: 1 I: 0 L: 1 K: 1 M: 0 F: 1 P: 2 S: 1 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
20
C116H180N42O28S2
2675.09
11.18
+5
5.83
-1.910
Evidence Records 1 records
Evidence 1 Activity

Activity

1.75% Hemolysis
Toxicity
25-100 µM
Hemolytic Cytotoxic
1.75% Hemolysis | 25-100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020