Back to search

Peptide record

TPDB09644

Antibacterial Antifungal Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09644
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 20-aa standard-residue multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KRKLIFLAAFLAALALFKKR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C114H192N30O21
NDCEQGHMPSTWYV
AL
2318.97
12.44
6
0
14
+6
0.23
0.815
142.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
5
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
5
L
4
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 5 K: 4 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20 reviewed residue count
C114H192N30O21 sequence-only estimate (linear, free termini)
2318.97 sequence-only estimate (linear, free termini)
12.44 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
0.23 sequence-only estimate (linear, free termini)
0.815 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
<20 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | <20 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De-novo design of antimicrobial peptides for plant protection. | PLoS One | 2013
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis