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Peptide record

TPDB09628

Maximin H1 Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09628
Maximin H1
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP dbAMP 3.0 iACP-DRLF pep-lab AFP-GFuse Antifungipept CAFPdb AI4AVP DRAVP 2.0 APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILGPVISTIGGVLGGLLKNL
Physicochemical Analysis
C90H160N22O24
ARDCEQHMFWY
GL
1934.39
10.10
1
0
10
+1
-1.41
1.420
185.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
5
G
0
H
3
I
5
L
1
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 3 L: 5 K: 1 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C90H160N22O24
1934.39
10.10
+1
-1.41
1.420
Free
L
Not Available
Free
Antibacterial
Bombina maxima
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC25922 (MIC 9 ug/ml), S. aureus ATCC2592 (4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not de
Evidence 2 Activity

Activity

MIC
Antibacterial
4.5 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP

Other

(4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not detectable), and fungi C. albicans ATCC2002 (MIC 4.5 ug/ml) (Lai R et al., 2012) . Updated 12/2015 11/2024.
Evidence 3 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2002

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.
Evidence 4 Activity

Activity

MIC
Antifungal
9 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC25922 (MIC 9 ug/ml), S. aureus ATCC2592 (4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not de
Evidence 5 Activity

Activity

MIC
Antifungal
4.5 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not detectable), and fungi C. albicans ATCC2002 (MIC 4.5 ug/ml) (Lai R et al., 2012) . Updated 12/2015 11/2024.
Evidence 6 Activity

Activity

MIC
Antiparasitic
9 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli ATCC25922 (MIC 9 ug/ml), S. aureus ATCC2592 (4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not de
Evidence 7 Activity

Activity

MIC
Antiparasitic
4.5 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP 3.0 DRAMP

Other

(4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not detectable), and fungi C. albicans ATCC2002 (MIC 4.5 ug/ml) (Lai R et al., 2012) . Updated 12/2015 11/2024.
Evidence 8 Activity

Activity

MIC
Antiviral
9 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against E. coli ATCC25922 (MIC 9 ug/ml), S. aureus ATCC2592 (4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not de
Evidence 9 Activity

Activity

MIC
Antiviral
4.5 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

(4.5 ug/ml), B. pyocyaneus CMCCB1010 (9 ug/ml), B.dysenteriae (not detectable), and fungi C. albicans ATCC2002 (MIC 4.5 ug/ml) (Lai R et al., 2012) . Updated 12/2015 11/2024.
Evidence 10 Activity

Activity

% Hemolysis
Hemolysis
100 %
[Ref:11835991]90–100% hemolytic activity at 50 µg/ml against rabbit red blood cells

Target

rabbit red blood cells

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 11 Activity

Activity

100% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 50 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. | Peptides | 2002
Evidence 12 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:11835991]90–100% hemolytic activity at 50 µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.
Evidence 13 Hemolysis

Activity

100 %
% Hemolysis
[Ref:11835991]90–100% hemolytic activity at 50 µg/ml against rabbit red blood cells
Hemolysis

Target

rabbit red blood cells

Source & Reference

APD_complete PD_Hemolysis
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.