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Peptide record

TPDB09616

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09616
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FVGAIAAALPHVISAIKNAL
Physicochemical Analysis
C93H154N24O23
RDCEQMTWY
A
1976.39
10.10
2
0
14
+1
-1.10
1.485
156.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
6
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
3
I
2
L
1
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 3 L: 2 K: 1 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C93H154N24O23
1976.39
10.10
+1
-1.10
1.485
Evidence Records 8 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus. At the same concentration, the peptide can cause hemolysis (horse blood) by ~50%. UPdated 5/2020
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus. At the same concentration, the peptide can cause hemolysis (horse blood) by ~50%. UPdated 5/2020
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against S. aureus. At the same concentration, the peptide can cause hemolysis (horse blood) by ~50%. UPdated 5/2020
Evidence 4 Activity

Activity

% Hemolysis
Hemolysis
18 50 %
[Ref:19427345]18% hemolytic activity at 16 µM, 45–50% hemolytic activity at 120 µM against horse erythrocytes

Target

horse erythrocytes

Source & Reference

Hemolytik APD_complete APD_hemolytic PD_Hemolysis
DRAMP4
Peptides. 2009 Aug 30(8):1428-1433.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
120 µM
Hemolytic Cytotoxic
50% Hemolysis | 120 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
A family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata. | Peptides | 2009
Evidence 6 Activity

Activity

18% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
18% Hemolysis | 16 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
A family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata. | Peptides | 2009
Evidence 7 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:19427345]18% hemolytic activity at 16 µM, 45–50% hemolytic activity at 120 µM against horse erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2009 Aug 30(8):1428-1433.
Evidence 8 Hemolysis

Activity

18 50 %
% Hemolysis
[Ref:19427345]18% hemolytic activity at 16 µM, 45–50% hemolytic activity at 120 µM against horse erythrocytes
Hemolysis

Target

horse erythrocytes

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
Peptides. 2009 Aug 30(8):1428-1433.
DRAMP4
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.