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Peptide record

TPDB09612

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09612
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 SATPdb iACP-DRLF Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
WLRRIGKGVKIIGGAALDHL
Physicochemical Analysis
C100H169N31O23
NCEQMFPSTY
G
2173.64
11.47
5
1
10
+3
1.10
0.335
141.50
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
253.03
0
Residue Composition
number
2
A
2
R
0
N
1
D
0
C
0
E
0
Q
4
G
1
H
3
I
3
L
2
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 4 H: 1 I: 3 L: 3 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
20
C100H169N31O23
2173.64
11.47
+3
1.10
0.335
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. | Dis Model Mech | 2011
Evidence 2 Activity

Activity

0% Killing
Toxicity
25 µM
Cytotoxic
0% Killing | 25 | µM | target cell: Zebrafish embryos

Target

Zebrafish embryos

Source & Reference

NA
DBAASP
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. | Dis Model Mech | 2011
Evidence 3 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.