Back to search

Peptide record

TPDB09609

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09609
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CancerPPD 2.0 dbACP Antifungipept CAFPdb AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILGPVLGLVSDTLDDVLGIL
Physicochemical Analysis
C93H160N20O29
ARNCEQHKMFWY
L
2022.41
2.82
0
3
11
-3
0.67
1.480
199.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
3
D
0
C
0
E
0
Q
3
G
0
H
2
I
6
L
0
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 3 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 6 K: 0 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
20
C93H160N20O29
2022.41
2.82
-3
0.67
1.480
Evidence Records 6 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
<250 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | <250 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
250-62.5 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 250-62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 3 Activity

Activity

50% Cell death
Toxicity
>49.4 µM
Cytotoxic
50% Cell death | >49.4 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010
Evidence 4 Activity

Activity

20% Hemolysis
Toxicity
90 µM
Hemolytic Cytotoxic
20% Hemolysis | 90 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The role of C-terminal amidation in the membrane interactions of the anionic antimicrobial peptide, maximin H5. | Biochim Biophys Acta | 2015
Evidence 5 Activity

Activity

1% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
1% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010
Evidence 6 Activity

Activity

12% Hemolysis
Toxicity
180 µM
Hemolytic Cytotoxic
12% Hemolysis | 180 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The role of C-terminal amidation in the membrane interactions of the anionic antimicrobial peptide, maximin H5. | Biochim Biophys Acta | 2015