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Peptide record

TPDB09608

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09608
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia dbAMP 3.0 Antifungipept CAFPdb AI4AVP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILGPVISKIGGVLGGLLKNL
Physicochemical Analysis
C92H165N23O23
ARDCEQHMFTWY
GL
1961.46
10.60
2
0
10
+2
-0.56
1.260
185.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
5
G
0
H
3
I
5
L
2
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 3 L: 5 K: 2 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C92H165N23O23
1961.46
10.60
+2
-0.56
1.260
Evidence Records 4 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
100 %
[Ref:11835991]90–100% hemolytic activity at 50 µg/ml against rabbit red blood cells

Target

rabbit red blood cells

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 50 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. | Peptides | 2002
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:11835991]90–100% hemolytic activity at 50 µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.
Evidence 4 Hemolysis

Activity

100 %
% Hemolysis
[Ref:11835991]90–100% hemolytic activity at 50 µg/ml against rabbit red blood cells
Hemolysis

Target

rabbit red blood cells

Source & Reference

APD_complete PD_Hemolysis
Eur J Immunol. 2005 Apr 35(4):1220-9.##Peptides. 2002 Mar 23(3):427-435.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.