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Peptide record

TPDB09607

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09607
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept APD_complete APD_hemolytic Hemolytic2
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IIGPVLGMVGSALGGLLKKI
Physicochemical Analysis
C90H162N22O22S1
RNDCEQHFTWY
G
1936.47
10.60
2
0
11
+2
-0.82
1.430
170.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
3
I
4
L
2
K
1
M
0
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 3 L: 4 K: 2 M: 1 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C90H162N22O22S1
1936.47
10.60
+2
-0.82
1.430
Evidence Records 7 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli D21 (LC 3.8 uM) and S. aureus Cowan 1 (LC 2.1 uM). (MIC data provided by Chunfeng Wang). Updated 9/2017 5/2020 7/2021 11/2023.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli D21 (LC 3.8 uM) and S. aureus Cowan 1 (LC 2.1 uM). (MIC data provided by Chunfeng Wang). Updated 9/2017 5/2020 7/2021 11/2023.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against E. coli D21 (LC 3.8 uM) and S. aureus Cowan 1 (LC 2.1 uM). (MIC data provided by Chunfeng Wang). Updated 9/2017 5/2020 7/2021 11/2023.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against E. coli D21 (LC 3.8 uM) and S. aureus Cowan 1 (LC 2.1 uM). (MIC data provided by Chunfeng Wang). Updated 9/2017 5/2020 7/2021 11/2023.
Evidence 5 Activity

Activity

Hemolysis
[Ref:8223491]Not determined hemolytic activity against human red blood cells.

Target

human red blood cells

Source & Reference

APD_complete APD_hemolytic
DRAMP4
EMBO J. 1993 Dec 12(12):4829-4832.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 6 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:8223491]Not determined hemolytic activity against human red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
EMBO J. 1993 Dec 12(12):4829-4832.
Evidence 7 Hemolysis

Activity

[Ref:8223491]Not determined hemolytic activity against human red blood cells.
Hemolysis

Target

human red blood cells

Source & Reference

APD_complete APD_hemolytic
EMBO J. 1993 Dec 12(12):4829-4832.
DRAMP4
APD_complete APD_hemolytic