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Peptide record

TPDB09605

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09605
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPLLLAGLPLKLCFLFKKC
Physicochemical Analysis
C114H185N23O21S2
RNDEQHIMSTWYV
L
2277.98
9.80
3
0
12
+3
-4.64
1.515
161.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
5.49
2
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
8
L
3
K
0
M
3
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 8 K: 3 M: 0 F: 3 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C114H185N23O21S2
2277.98
9.80
+3
-4.64
1.515
Evidence Records 4 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
59.39 %
[Ref:17698251] It has 59.39% hemolytic activity at 100 µg/ml against huamn red blood cells

Target

huamn red blood cells

Source & Reference

Hemolytik APD_complete APD_hemolytic PD_Hemolysis
DRAMP4
Peptides. 2007 Aug 28(8):1532-1539.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

59% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
59% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and characterization of antimicrobial peptides from the skin secretion of Rana dybowskii. | Peptides | 2007
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:17698251] It has 59.39% hemolytic activity at 100 µg/ml against huamn red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2007 Aug 28(8):1532-1539.
Evidence 4 Hemolysis

Activity

59.39 %
% Hemolysis
[Ref:17698251] It has 59.39% hemolytic activity at 100 µg/ml against huamn red blood cells
Hemolysis

Target

huamn red blood cells

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
Peptides. 2007 Aug 28(8):1532-1539.
DRAMP4
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.