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Peptide record

TPDB09601

Antibacterial Anticancer Antifungal Antiparasitic standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09601
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LAHQKPFIRKSYKCLHKRCR
Physicochemical Analysis
C112H186N38O24S2
NDEGMTWV
K
2513.07
11.00
9
0
6
+7
5.32
-1.050
63.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1615
64.26
5
Residue Composition
number
1
A
3
R
0
N
0
D
2
C
0
E
1
Q
0
G
2
H
1
I
2
L
4
K
0
M
1
F
1
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 0 H: 2 I: 1 L: 2 K: 4 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
20
C112H186N38O24S2
2513.07
11.00
+7
5.32
-1.050
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.43 µM

Target

S. gordonii

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
0 4.41 uM), S. mutans cariogenic bacteria (ED50 1.39 uM), P. gingivalis (ED50 <1 uM), and S. gordonii (MIC 2.43 uM), fungi C. albicans DIS or azole resistant (ED50 2.40-5.85 uM), C. glabrata or fluconazole
Evidence 2 Activity

Activity

MIC
Antibacterial
5.23 µM

Target

S. cerevisiae

Source & Reference

dbAMP DRAMP

Other

ED50 5.16 uM), and C. neoformans CN2 or amphotericin B resistant (ED50 4.05-4.29 uM), and S. cerevisiae (MIC 5.23 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
2.43 µM

Target

S. gordonii

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
0 4.41 uM), S. mutans cariogenic bacteria (ED50 1.39 uM), P. gingivalis (ED50 <1 uM), and S. gordonii (MIC 2.43 uM), fungi C. albicans DIS or azole resistant (ED50 2.40-5.85 uM), C. glabrata or fluconazole
Evidence 4 Activity

Activity

MIC
Antifungal
5.23 µM

Target

S. cerevisiae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ED50 5.16 uM), and C. neoformans CN2 or amphotericin B resistant (ED50 4.05-4.29 uM), and S. cerevisiae (MIC 5.23 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
2.43 µM

Target

S. gordonii

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
0 4.41 uM), S. mutans cariogenic bacteria (ED50 1.39 uM), P. gingivalis (ED50 <1 uM), and S. gordonii (MIC 2.43 uM), fungi C. albicans DIS or azole resistant (ED50 2.40-5.85 uM), C. glabrata or fluconazole
Evidence 6 Activity

Activity

MIC
Antiparasitic
5.23 µM

Target

S. cerevisiae

Source & Reference

DRAMP

Other

ED50 5.16 uM), and C. neoformans CN2 or amphotericin B resistant (ED50 4.05-4.29 uM), and S. cerevisiae (MIC 5.23 uM).