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Peptide record

TPDB09600

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09600
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept CAFPdb
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KWKLFKKIGIGKFLHSAKKF
Physicochemical Analysis
C120H190N30O22
RNDCEQMPTYV
K
2405.02
11.29
8
0
9
+7
0.89
-0.310
83.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
228.69
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
2
I
2
L
7
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 2 K: 7 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C120H190N30O22
2405.02
11.29
+7
0.89
-0.310
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

6% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
6% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The antimicrobial peptide CMA3 derived from the CA-MA hybrid peptide: antibacterial and anti-inflammatory activities with low cytotoxicity and mechanism of action in Escherichia coli | Antimicrob Agents Chemother | 2015
Evidence 3 Activity

Activity

85% Cytotoxicity
Toxicity
12.5 µM
Cytotoxic
85% Cytotoxicity | 12.5 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
The antimicrobial peptide CMA3 derived from the CA-MA hybrid peptide: antibacterial and anti-inflammatory activities with low cytotoxicity and mechanism of action in Escherichia coli | Antimicrob Agents Chemother | 2015