Peptide record

TPDB09592

Antibacterial Antifungal Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09592
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPFLLSALPKVFCFFSKKC
Physicochemical Analysis
C117H175N23O23S2
RNDEQGHIMTWY
F
2335.94
9.80
3
0
11
+3
-4.34
1.185
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
5.35
4
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
4
L
3
K
0
M
5
F
2
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 3 M: 0 F: 5 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C117H175N23O23S2
2335.94
9.80
+3
-4.34
1.185
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
50% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning and functional characterization of novel antimicrobial peptides from the skin of brown frog, Rana zhenhaiensis. | Zoolog Sci | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis