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Peptide record

TPDB09576

Antibacterial Anticancer Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09576
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILSKLGKALKKAAKHAAKA
Physicochemical Analysis
C91H166N28O22
RNDCEQMFPTWYV
AK
2004.49
11.21
7
0
10
+6
4.04
-0.075
108.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
1
I
3
L
6
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 1 L: 3 K: 6 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C91H166N28O22
2004.49
11.21
+6
4.04
-0.075
Evidence Records 3 records
Evidence 1 Activity

Activity

30% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
30% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. | Eur J Biochem | 1997
Evidence 2 Activity

Activity

<=50% Cell death
Toxicity
40 µM
Cytotoxic
<=50% Cell death | 40 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. | Eur J Biochem | 1997
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis