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Peptide record

TPDB09572

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09572
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILGPVIKTIGGVIGGLLKNL
Physicochemical Analysis
C93H167N23O23
ARDCEQHMFSWY
G
1975.49
10.60
2
0
10
+2
-0.30
1.300
185.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
5
G
0
H
4
I
4
L
2
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 4 L: 4 K: 2 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C93H167N23O23
1975.49
10.60
+2
-0.30
1.300
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.8 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), and B. subtilis ATCC 6633 (MIC 18.8ug/ml).
Evidence 2 Activity

Activity

MIC
Antifungal
18.8 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), and B. subtilis ATCC 6633 (MIC 18.8ug/ml).
Evidence 3 Activity

Activity

MIC
Antiparasitic
18.8 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), and B. subtilis ATCC 6633 (MIC 18.8ug/ml).
Evidence 4 Activity

Activity

33% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
33% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 5 Activity

Activity

10% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 6 Activity

Activity

3% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 7 Activity

Activity

2% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 8 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.