Peptide record

TPDB09568

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09568
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 i2APP ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KIKIPWGKVKDFLVGGMKAV
Physicochemical Analysis
C106H176N26O23S1
RNCEQHSTY
K
2214.78
10.71
5
1
10
+4
2.31
0.260
107.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
248.33
0
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
2
I
1
L
5
K
1
M
1
F
1
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 1 K: 5 M: 1 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
20
C106H176N26O23S1
2214.78
10.71
+4
2.31
0.260
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
24.4 µM

Target

Escherichia coli CIP 7624

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. xylosus and S. aureus. Also: Gram- E. coli CIP 7624 (MIC 24.4 uM), C. sakazakii ATCC 29544 (MIC 5.8), P. aeruginosa CIP 82118, P. aeruginosa CIP 82118 (MIC
Evidence 2 Activity

Activity

MIC
Antifungal
24.4 µM

Target

Escherichia coli CIP 7624

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. xylosus and S. aureus. Also: Gram- E. coli CIP 7624 (MIC 24.4 uM), C. sakazakii ATCC 29544 (MIC 5.8), P. aeruginosa CIP 82118, P. aeruginosa CIP 82118 (MIC
Evidence 3 Activity

Activity

MIC
Antiparasitic
24.4 µM

Target

Escherichia coli CIP 7624

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Active against S. xylosus and S. aureus. Also: Gram- E. coli CIP 7624 (MIC 24.4 uM), C. sakazakii ATCC 29544 (MIC 5.8), P. aeruginosa CIP 82118, P. aeruginosa CIP 82118 (MIC
Evidence 4 Activity

Activity

10% Hemolysis
Toxicity
180 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 180 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of a novel antimicrobial peptide from the venom of the ant Tetramorium bicarinatum. | Peptides | 2012
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
720 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 720 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of a novel antimicrobial peptide from the venom of the ant Tetramorium bicarinatum. | Peptides | 2012