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Peptide record

TPDB09567

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09567
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
GSKKPVPIIYCNRRGKCQRM
Physicochemical Analysis
C99H172N34O25S3
ADEHLFTW
RK
2334.85
10.88
6
0
5
+6
5.25
-0.910
53.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
69.17
6
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
1
Q
2
G
0
H
2
I
0
L
3
K
1
M
0
F
2
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 0 K: 3 M: 1 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
20
C99H172N34O25S3
2334.85
10.88
+6
5.25
-0.910
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.64 µM

Target

Escherichia coli HB 101

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S
Evidence 2 Activity

Activity

MIC
Antibacterial
1.3 µM

Target

S. typhimurium

Source & Reference

dbAMP

Other

active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
2.6 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
5.2 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

st E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
10.4 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
0.64 µM

Target

Escherichia coli HB 101

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S
Evidence 7 Activity

Activity

MIC
Antifungal
1.3 µM

Target

S. typhimurium

Source & Reference

dbAMP

Other

active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
2.6 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
5.2 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

st E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
10.4 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
0.64 µM

Target

Escherichia coli HB 101

Source & Reference

NA

Other

active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S
Evidence 12 Activity

Activity

MIC
Antiparasitic
1.3 µM

Target

S. typhimurium

Source & Reference

NA

Other

active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 13 Activity

Activity

MIC
Antiparasitic
2.6 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

active against E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 14 Activity

Activity

MIC
Antiparasitic
5.2 µM

Target

B. subtilis

Source & Reference

NA

Other

st E. coli HB 101 (MIC 0.64 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 15 Activity

Activity

MIC
Antiparasitic
10.4 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 2.6 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 16 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Role of amino acid residues within the disulfide loop of thanatin, a potent antibiotic peptide. | J Biochem Mol Biol | 2002