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Peptide record

TPDB09559

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09559
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IIGAIAAALPHVINAIKNTF
Physicochemical Analysis
C96H159N25O24
RDCEQMSWY
AI
2047.47
10.10
2
0
13
+1
-0.63
1.275
156.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
5
A
0
R
2
N
0
D
0
C
0
E
0
Q
1
G
1
H
5
I
1
L
1
K
0
M
1
F
1
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 5 L: 1 K: 1 M: 0 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C96H159N25O24
2047.47
10.10
+1
-0.63
1.275
Evidence Records 9 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against S. aureus.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against S. aureus.
Evidence 5 Activity

Activity

% Hemolysis
Hemolysis
18 50 %
[Ref:19427345]18% hemolytic activity at 16 µM, 45–50% hemolytic activity at 120 µM against horse erythrocytes

Target

horse erythrocytes

Source & Reference

Hemolytik APD_complete APD_hemolytic PD_Hemolysis
DRAMP4
Peptides. 2009 Aug 30(8):1428-1433.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
120 µM
Hemolytic Cytotoxic
50% Hemolysis | 120 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
A family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata. | Peptides | 2009
Evidence 7 Activity

Activity

18% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
18% Hemolysis | 16 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
A family of kassinatuerin-2 related peptides from the skin secretion of the African hyperoliid frog, Kassina maculata. | Peptides | 2009
Evidence 8 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:19427345]18% hemolytic activity at 16 µM, 45–50% hemolytic activity at 120 µM against horse erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2009 Aug 30(8):1428-1433.
Evidence 9 Hemolysis

Activity

18 50 %
% Hemolysis
[Ref:19427345]18% hemolytic activity at 16 µM, 45–50% hemolytic activity at 120 µM against horse erythrocytes
Hemolysis

Target

horse erythrocytes

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
Peptides. 2009 Aug 30(8):1428-1433.
DRAMP4
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.