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Peptide record

TPDB09538

Antibacterial Antifungal Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09538
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept APD_complete PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLDFLKAAGKGLVSNLLEK
Physicochemical Analysis
C96H164N24O27
RCQHIMPTWY
L
2086.50
9.76
3
2
10
+1
2.04
0.460
141.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
1
D
0
C
1
E
0
Q
3
G
0
H
0
I
6
L
3
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 0 L: 6 K: 3 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C96H164N24O27
2086.50
9.76
+1
2.04
0.460
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
15 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against t E. coli ATCC 25922 (MIC 15 uM) and S. aureus ATCC 25923 (MIC 15 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
15 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP

Other

Active against t E. coli ATCC 25922 (MIC 15 uM) and S. aureus ATCC 25923 (MIC 15 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
15 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against t E. coli ATCC 25922 (MIC 15 uM) and S. aureus ATCC 25923 (MIC 15 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
15 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against t E. coli ATCC 25922 (MIC 15 uM) and S. aureus ATCC 25923 (MIC 15 uM).
Evidence 5 Activity

Activity

100% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
100% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Leptodactylus latrans Amphibian Skin Secretions as a Novel Source for the Isolation of Antibacterial Peptides. | Molecules | 2018
Evidence 6 Activity

Activity

MHC
Toxicity
40 µM
Hemolytic
Hemolytic_activity: [Ref.30423858] 100% hemolysis MHC=40µM against human blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Molecules. 2018 Nov 23(11): 2943. Published online 2018 Nov 11. doi: 10.3390/molecules23112943
Evidence 7 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.