Back to search

Peptide record

TPDB09532

Antibacterial Antifungal Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09532
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KRRLIARILRLAARALVKKR
Physicochemical Analysis
C107H205N41O21
NDCEQGHMFPSTWY
R
2402.07
13.10
9
0
11
+9
4.36
-0.155
151.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
4
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C107H205N41O21
2402.07
13.10
+9
4.36
-0.155
Evidence Records 3 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De-novo design of antimicrobial peptides for plant protection. | PLoS One | 2013
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
50% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A de novo-designed antimicrobial peptide with activity against multiresistant Staphylococcus aureus acting on RsbW kinase. | FASEB J | 2013
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis