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Peptide record

TPDB09531

Antibacterial Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09531
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KRRLFLFRLFRLFLRLFLKK
Physicochemical Analysis
C135H220N38O21
ANDCEQGHIMPSTWYV
L
2711.47
13.01
8
0
12
+8
-2.55
0.320
136.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
7
L
3
K
0
M
5
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 7 K: 3 M: 0 F: 5 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C135H220N38O21
2711.47
13.01
+8
-2.55
0.320
Evidence Records 3 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De-novo design of antimicrobial peptides for plant protection. | PLoS One | 2013
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
50% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A de novo-designed antimicrobial peptide with activity against multiresistant Staphylococcus aureus acting on RsbW kinase. | FASEB J | 2013
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis