Back to search

Peptide record

TPDB09525

Antibacterial Anticancer Antifungal Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09525
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
NRFTARFRRTPWRLCLQFRQ
Physicochemical Analysis
C119H186N42O26S1
DEGHIKMSYV
R
2653.11
12.70
6
0
7
+6
0.40
-1.055
44.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
5500
207.30
6
Residue Composition
number
1
A
6
R
1
N
0
D
1
C
0
E
2
Q
0
G
0
H
0
I
2
L
0
K
0
M
3
F
1
P
0
S
2
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 6 N: 1 D: 0 C: 1 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 3 P: 1 S: 0 T: 2 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C119H186N42O26S1
2653.11
12.70
+6
0.40
-1.055
Evidence Records 4 records
Evidence 1 Activity

Activity

LC50
Toxicity
>128 µg/mL
Cytotoxic
LC50 | >128 | µg/mL | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
The rumen microbiome: an underexplored resource for novel antimicrobial discovery. | NPJ Biofilms Microbiomes | 2017
Evidence 2 Activity

Activity

45% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
45% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The rumen microbiome: an underexplored resource for novel antimicrobial discovery. | NPJ Biofilms Microbiomes | 2017
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 500 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The rumen microbiome: an underexplored resource for novel antimicrobial discovery. | NPJ Biofilms Microbiomes | 2017
Evidence 4 Activity

Activity

LC50
Toxicity
128 µg/mL
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 45% Hemolysis=500µg/ml Sheep erythrocytes: 0% Hemolysis=500µg/ml | Cytotoxicity: HUVEC: LC50>128µg/ml

Target

erythrocytes

Source & Reference

NA
DRAMP
NPJ Biofilms Microbiomes. 2017 Dec 1 3:33.