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Peptide record

TPDB09507

Antibacterial Antifungal Antiparasitic Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09507
Antibacterial Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP dbAMP 3.0 PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FFFHIVKGLFHAGRMIHGLV
Physicochemical Analysis
C114H168N30O21S1
NDCEQPSTWY
F
2326.84
11.49
5
0
12
+2
-1.81
1.035
112.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
3
G
3
H
2
I
2
L
1
K
1
M
4
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 3 I: 2 L: 2 K: 1 M: 1 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C114H168N30O21S1
2326.84
11.49
+2
-1.81
1.035
Evidence Records 5 records
Evidence 1 Activity

Activity

5.12±0.37% Hemolysis
Toxicity
2.5 µM
Hemolytic Cytotoxic
5.12±0.37% Hemolysis | 2.5 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 2 Activity

Activity

8.22±0.87% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
8.22±0.87% Hemolysis | 5 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 3 Activity

Activity

17.11±1.90% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
17.11±1.90% Hemolysis | 10 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 4 Activity

Activity

26.52±1.87% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
26.52±1.87% Hemolysis | 20 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis