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Peptide record

TPDB09498

Antibacterial Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09498
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KIAKGALKALKIAKVALKAL
Physicochemical Analysis
C97H182N26O21
RNDCEQHMFPSTWY
AK
2048.67
11.21
6
0
13
+6
2.14
0.770
161.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
4
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 4 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C97H182N26O21
2048.67
11.21
+6
2.14
0.770
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
30±3 µM
Hemolytic Cytotoxic
50% Hemolysis | 30±3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity Affected by the Conformational Flexibility in Glycine-Lysine Based ?-Helical Antimicrobial Peptides. | J Med Chem | 2018
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis