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Peptide record

TPDB09497

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09497
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KIAKGALKALKIAKGALKAL
Physicochemical Analysis
C94H176N26O21
RNDCEQHMFPSTWYV
AK
2006.59
11.21
6
0
12
+6
2.08
0.540
147.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
4
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C94H176N26O21
2006.59
11.21
+6
2.08
0.540
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
100±5 µM
Hemolytic Cytotoxic
50% Hemolysis | 100±5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity Affected by the Conformational Flexibility in Glycine-Lysine Based ?-Helical Antimicrobial Peptides. | J Med Chem | 2018