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Peptide record

TPDB09492

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09492
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IASKVANTVQKLKRKAKNAV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C95H175N31O26
DCEGHMFPWY
K
2167.63
11.85
6
0
9
+6
1.91
-0.395
102.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
5
Residue Composition
number
4
A
1
R
2
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
5
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 5 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
20 reviewed residue count
C95H175N31O26 sequence-only estimate (linear, free termini)
2167.63 sequence-only estimate (linear, free termini)
11.85 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
1.91 sequence-only estimate (linear, free termini)
-0.395 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
2% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. | Biochim Biophys Acta | 2013