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Peptide record

TPDB09476

Antibacterial Antifungal Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09476
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GKILKYLLYLLRKYANLIIR
Physicochemical Analysis
C120H202N30O25
DCEQHMFPSTWV
L
2465.11
10.63
5
0
13
+5
-2.26
0.480
180.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
4470
181.33
4
Residue Composition
number
1
A
2
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
6
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 6 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
20
C120H202N30O25
2465.11
10.63
+5
-2.26
0.480
Evidence Records 7 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
1-4 µM
Hemolytic Cytotoxic
0% Hemolysis | 1-4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 2 Activity

Activity

2.89±1.12% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
2.89±1.12% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 3 Activity

Activity

6.30±1.59% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
6.30±1.59% Hemolysis | 16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 4 Activity

Activity

17.39±1.15% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
17.39±1.15% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 5 Activity

Activity

29.15±2.57% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
29.15±2.57% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 6 Activity

Activity

50.15±5.15% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
50.15±5.15% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 7 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis