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Peptide record

TPDB09458

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09458
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FRIRVRVFKRIVQRIKDFLR
Physicochemical Analysis
C123H209N41O24
ANCEGHMPSTWY
R
2646.27
12.71
8
1
10
+7
3.98
-0.175
121.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
6
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
3
I
1
L
2
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 3 L: 1 K: 2 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
20
C123H209N41O24
2646.27
12.71
+7
3.98
-0.175
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
<5% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
High Specific Selectivity and Membrane-Active Mechanism of Synthetic Cationic Hybrid Antimicrobial Peptides Based on the Peptide FV7. | Int J Mol Sci | 2017
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
2 %
Hemolytic
Hemolytic_activity: [Ref.28178190] 2% hemolysis at 128 µM against human red cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Int J Mol Sci. 2017 Feb 6 18(2).