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Peptide record

TPDB09455

Antibacterial standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09455
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard-residue antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FLPVLVKVFRYSKKTAAGCF
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C110H172N26O24S1
NDEQHIMW
KFV
2274.80
10.46
4
0
11
+4
0.05
0.685
92.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
0.66
4
Residue Composition
number
2
A
1
R
0
N
0
D
1
C
0
E
0
Q
1
G
0
H
0
I
2
L
3
K
0
M
3
F
1
P
1
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 3 M: 0 F: 3 P: 1 S: 1 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
20 reviewed residue count
C110H172N26O24S1 sequence-only estimate (linear, free termini)
2274.80 sequence-only estimate (linear, free termini)
10.46 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
0.05 sequence-only estimate (linear, free termini)
0.685 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

E.coli

Source & Reference

NA

Other

Active against E.coli (MIC >128 ug/ml) and B. cereus (MIC 64 ug/ml). Warning: other bacteria not tested.
Evidence 2 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

B. cereus

Source & Reference

NA

Other

Active against E.coli (MIC >128 ug/ml) and B. cereus (MIC 64 ug/ml). Warning: other bacteria not tested.