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Peptide record

TPDB09413

Antibacterial Antifungal Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09413
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LALRTAGWLRLLGFRDKKKN
Physicochemical Analysis
C108H182N34O25
CEQHIMPSYV
L
2356.85
12.14
6
1
9
+5
1.09
-0.460
107.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
233.36
2
Residue Composition
number
2
A
3
R
1
N
1
D
0
C
0
E
0
Q
2
G
0
H
0
I
5
L
3
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 5 K: 3 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C108H182N34O25
2356.85
12.14
+5
1.09
-0.460
Evidence Records 3 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 32 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017
Evidence 2 Activity

Activity

<10% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 128 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017
Evidence 3 Activity

Activity

30% Killing
Toxicity
32-256 µg/mL
Cytotoxic
30% Killing | 32-256 | µg/mL | target cell: Monkey COS-7 cells

Target

Monkey COS-7 cells

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017