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Peptide record

TPDB09390

Antibacterial Anticancer Cell-penetrating Peptides Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09390
Antibacterial Anticancer Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CancerPPD 2.0 CPPsite3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
WRRRYRRWRRRRRWRRRPRR
Physicochemical Analysis
C137H228N68O22
ANDCEQGHILKMFSTV
R
3179.76
13.21
15
0
4
+15
6.11
-3.655
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
17990
565.77
1
Residue Composition
number
0
A
15
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
3
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 15 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 3 Y: 1 V: 0
Chemical Descriptors
20
C137H228N68O22
3179.76
13.21
+15
6.11
-3.655
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
To What Extent Do Fluorophores Bias the Biological Activity of Peptides? A Practical Approach Using Membrane-Active Peptides as Models. | Front Bioeng Biotechnol | 2020
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis>200µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Front Bioeng Biotechnol. 2020 Sep 9 8:552035