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Peptide record

TPDB09291

vCPP 0417 vCPP0417 Antibacterial Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09291
vCPP 0417 vCPP0417
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
SPRRRTPSPRRRRSQSPRRR-NH2
Physicochemical Analysis
C101H185N51O27
ANDCEGHILKMFWYV
R
2545.91
13.35
10
0
0
+10
11.14
-2.940
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
0
A
10
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
4
P
4
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 4 S: 4 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C101H185N51O27
2545.91
13.35
+10
11.14
-2.940
Amidation
L
Linear
Free
N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MDA-MB-231 And BT-20 Cells BT-474 And SKBR3 Cells MCF 10A And HS68 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
In vitro
CBCCBTTBCCBCCCBTTBCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Staphylococcus aureus (S. aureus) and MRSA, Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa)

Source & Reference

CPPsite3.0
CPPsite3

Other

Non-natural residues Linear L
Protein derived
In vitro
Additional Detail Fields 1 fields
CBCCBTTBCCBCCCBTTBCC