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Peptide record

TPDB09277

Antibacterial Antifungal Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB09277
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
AKKVFKRLGIGAVLWVLTTG
Physicochemical Analysis
C103H173N27O23
NDCEQHMPSY
GLKV
2157.67
11.73
4
0
11
+4
-1.01
0.760
131.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
254.90
2
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
3
L
3
K
0
M
1
F
0
P
0
S
2
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 3 M: 0 F: 1 P: 0 S: 0 T: 2 W: 1 Y: 0 V: 3
Chemical Descriptors
20
C103H173N27O23
2157.67
11.73
+4
-1.01
0.760
Evidence Records 6 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
6.25 µM
Hemolytic Cytotoxic
0% Hemolysis | 6.25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12). | Biotechnol Lett | 2004
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
1% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12). | Biotechnol Lett | 2004
Evidence 3 Activity

Activity

13% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
13% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12). | Biotechnol Lett | 2004
Evidence 4 Activity

Activity

30% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
30% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12). | Biotechnol Lett | 2004
Evidence 5 Activity

Activity

46% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
46% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12). | Biotechnol Lett | 2004
Evidence 6 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis