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Peptide record

TPDB09242

Antibacterial Antifungal Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09242
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 19-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KKAAHVGKHVGKAALTHYL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C93H153N29O22
RNDCEQIMFPSW
AK
2029.42
10.64
7
0
9
+4
0.62
-0.253
92.63
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
0.73
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
3
H
0
I
2
L
4
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 3 I: 0 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
19 reviewed residue count
C93H153N29O22 sequence-only estimate (linear, free termini)
2029.42 sequence-only estimate (linear, free termini)
10.64 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
0.62 sequence-only estimate (linear, free termini)
-0.253 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
3.13-100 µM
Hemolytic Cytotoxic
0% Hemolysis | 3.13-100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of the hydrophobic amino acids in the N- and C-terminal regions of pleurocidin on antifungal activity. | J Microbiol Biotechnol | 2010