Peptide record

TPDB09237

Antibacterial Anticancer Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09237
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RVKRVWPLVIRTVIAGYNL
Physicochemical Analysis
C106H177N31O23
DCEQHMFS
V
2253.77
12.12
4
0
11
+4
0.02
0.495
148.42
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6990
310.15
3
Residue Composition
number
1
A
3
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
1
K
0
M
0
F
1
P
0
S
1
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 1 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 1 V: 4
Chemical Descriptors
19
C106H177N31O23
2253.77
12.12
+4
0.02
0.495
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
10% Hemolysis | >256 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The design of a cell-selective fowlicidin-1-derived peptide with both antimicrobial and anti-inflammatory activities. | Eur J Med Chem | 2019