Back to search

Peptide record

TPDB09216

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09216
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb i2APP
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GPVGLLSSPGSLPPVGGAP
Physicochemical Analysis
C75H123N19O23
RNDCEQHIKMFTWY
GP
1658.92
6.02
0
0
6
-0
0.98
0.484
97.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
0
I
3
L
0
K
0
M
0
F
5
P
3
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 5 S: 3 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
19
C75H123N19O23
1658.92
6.02
-0
0.98
0.484
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Diffusion assays (20 ug peptide): Active against B. subtilis (inhibition diameter: 19.04 mm), X. campestris pv. Vesicatoria (16.47 mm), P. solanacearum (10.75 mm), P. wickerhami (10.3 mm), B. megaterium (7.3 mm). Active against fungi: P. capsici (23.06% inhibition), V. dahliae (52.46% inhibition), F. graminearum (23.94% inhibition), and F. omysporum (14.6% inhibition). Interstingly, the same peptide has also been identified in Lactobacillus crustorum MN047 ( Yi et al., 2018 ). Inhibition zone assays reveal broad-spectrum activity. active against Gram+ S. aureus ATCC 29213, 25923 (19.1-19.2 mm), E. faecalis ATCC 29212 (10.3 mm), L. monocytogenes CMCC 54004 (17.2 mm), Gram- E. coli ATCC 25922 (17.0 mm), Salmonella CMCC 50071 (18.7 mm), C. sakazakii ATCC 29544 (18 mm), also active against antibiotic0resistant C. sakazakii (16.9-18.4 mm) and Salmonella 557D (15.6 mm). Found in multiple species. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Diffusion assays (20 ug peptide): Active against B. subtilis (inhibition diameter: 19.04 mm), X. campestris pv. Vesicatoria (16.47 mm), P. solanacearum (10.75 mm), P. wickerhami (10.3 mm), B. megaterium (7.3 mm). Active against fungi: P. capsici (23.06% inhibition), V. dahliae (52.46% inhibition), F. graminearum (23.94% inhibition), and F. omysporum (14.6% inhibition). Interstingly, the same peptide has also been identified in Lactobacillus crustorum MN047 ( Yi et al., 2018 ). Inhibition zone assays reveal broad-spectrum activity. active against Gram+ S. aureus ATCC 29213, 25923 (19.1-19.2 mm), E. faecalis ATCC 29212 (10.3 mm), L. monocytogenes CMCC 54004 (17.2 mm), Gram- E. coli ATCC 25922 (17.0 mm), Salmonella CMCC 50071 (18.7 mm), C. sakazakii ATCC 29544 (18 mm), also active against antibiotic0resistant C. sakazakii (16.9-18.4 mm) and Salmonella 557D (15.6 mm). Found in multiple species. Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Diffusion assays (20 ug peptide): Active against B. subtilis (inhibition diameter: 19.04 mm), X. campestris pv. Vesicatoria (16.47 mm), P. solanacearum (10.75 mm), P. wickerhami (10.3 mm), B. megaterium (7.3 mm). Active against fungi: P. capsici (23.06% inhibition), V. dahliae (52.46% inhibition), F. graminearum (23.94% inhibition), and F. omysporum (14.6% inhibition). Interstingly, the same peptide has also been identified in Lactobacillus crustorum MN047 ( Yi et al., 2018 ). Inhibition zone assays reveal broad-spectrum activity. active against Gram+ S. aureus ATCC 29213, 25923 (19.1-19.2 mm), E. faecalis ATCC 29212 (10.3 mm), L. monocytogenes CMCC 54004 (17.2 mm), Gram- E. coli ATCC 25922 (17.0 mm), Salmonella CMCC 50071 (18.7 mm), C. sakazakii ATCC 29544 (18 mm), also active against antibiotic0resistant C. sakazakii (16.9-18.4 mm) and Salmonella 557D (15.6 mm). Found in multiple species. Updated 7/2021
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Diffusion assays (20 ug peptide): Active against B. subtilis (inhibition diameter: 19.04 mm), X. campestris pv. Vesicatoria (16.47 mm), P. solanacearum (10.75 mm), P. wickerhami (10.3 mm), B. megaterium (7.3 mm). Active against fungi: P. capsici (23.06% inhibition), V. dahliae (52.46% inhibition), F. graminearum (23.94% inhibition), and F. omysporum (14.6% inhibition). Interstingly, the same peptide has also been identified in Lactobacillus crustorum MN047 ( Yi et al., 2018 ). Inhibition zone assays reveal broad-spectrum activity. active against Gram+ S. aureus ATCC 29213, 25923 (19.1-19.2 mm), E. faecalis ATCC 29212 (10.3 mm), L. monocytogenes CMCC 54004 (17.2 mm), Gram- E. coli ATCC 25922 (17.0 mm), Salmonella CMCC 50071 (18.7 mm), C. sakazakii ATCC 29544 (18 mm), also active against antibiotic0resistant C. sakazakii (16.9-18.4 mm) and Salmonella 557D (15.6 mm). Found in multiple species. Updated 7/2021