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Peptide record

TPDB09211

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09211
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
CVISAGWNHKIRCKLTGNC
Physicochemical Analysis
C89H147N29O24S3
DEQMFPY
C
2103.51
9.21
4
0
6
+3
1.03
0.032
82.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
267.41
7
Residue Composition
number
1
A
1
R
2
N
0
D
3
C
0
E
0
Q
2
G
1
H
2
I
1
L
2
K
0
M
0
F
0
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 0 C: 3 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 1 K: 2 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
19
C89H147N29O24S3
2103.51
9.21
+3
1.03
0.032
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus aureus ATCC43300

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP DRAMP

Other

ive against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 3 Activity

Activity

MIC
Antifungal
50 µM

Target

Staphylococcus aureus ATCC43300

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 4 Activity

Activity

MIC
Antifungal
25 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ive against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 5 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Staphylococcus aureus ATCC43300

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 6 Activity

Activity

MIC
Antiparasitic
25 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

DRAMP

Other

ive against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 7 Activity

Activity

MIC
Antiviral
50 µM

Target

Staphylococcus aureus ATCC43300

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 8 Activity

Activity

MIC
Antiviral
25 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

DRAMP

Other

ive against S. aureus ATCC25923 or S. aureus ATCC43300 (MIC 50 uM), P. aeruginosa PA01 or P. aeruginosa ATCC27853 (MIC 25 uM). updated 5/2019 7/2020.
Evidence 9 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010
Evidence 10 Activity

Activity

(15.04±2.29)% Degranulation
Toxicity
50 µg/mL
Cytotoxic
(15.04±2.29)% Degranulation | 50 | µg/mL | target cell: Rat mast cells

Target

Rat mast cells

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010