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Peptide record

TPDB09207

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09207
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 APD_complete Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSLIPHIVSGVASIAKHF
Physicochemical Analysis
C98H154N24O23
RNDCEQMTWY
IS
2036.45
10.10
3
0
11
+1
-0.75
1.263
143.68
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
2
H
3
I
2
L
1
K
0
M
2
F
1
P
3
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 2 I: 3 L: 2 K: 1 M: 0 F: 2 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
19
C98H154N24O23
2036.45
10.10
+1
-0.75
1.263
Evidence Records 3 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
7% Hemolysis | 5 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Phylloseptin-1 (PSN-1) from Phyllomedusa sauvagei skin secretion: a novel broad-spectrum antimicrobial peptide with antibiofilm activity. | Mol Immunol | 2010
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
39 µM
Hemolytic Cytotoxic
50% Hemolysis | 39 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure, antimicrobial activities and mode of interaction with membranes of novel [corrected] phylloseptins from the painted-belly leaf frog, Phyllomedusa sauvagii. | PLoS One | 2013
Evidence 3 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.